University > Health Conditions > Exocrine Pancreatic Insufficiency (EPI)
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Exocrine Pancreatic Insufficiency (EPI)

EPI is a condition where the pancreas fails to produce enough digestive enzymes, leading to nutrient malabsorption, chronic diarrhea, and weight loss despite a good appetite. Lifelong enzyme supplementation and a highly digestible diet are essential for management.
Last Reviewed Date: 01/12/2026

Overview

General Health Topics

Info Health Topics related to Exocrine Pancreatic Insufficiency (EPI)
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Therapeutic Interventions

Info Therapeutic Interventions of Exocrine Pancreatic Insufficiency (EPI)

Lifestyle Strategies

Info Lifestyle Strategies of Exocrine Pancreatic Insufficiency (EPI)

Foods

Info Food sources of Exocrine Pancreatic Insufficiency (EPI)

Food Components

Info Ingredient sources of Exocrine Pancreatic Insufficiency (EPI)

Food Component Groups

Info Ingredient sources group of Exocrine Pancreatic Insufficiency (EPI)
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Nutrients

Info Nutrients Found in Exocrine Pancreatic Insufficiency (EPI)
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Nutrient Types

Info Nutrient Types of Exocrine Pancreatic Insufficiency (EPI)
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Nutrient Sub-Types

Info Nutrient Sub-Types of Exocrine Pancreatic Insufficiency (EPI)

Follow the Research

Info Studies providing deeper insight into Exocrine Pancreatic Insufficiency (EPI)
Title Information
Chronic Diarrhea in Dogs – Retrospective Study in 136 Cases

At a Glance

This 2017 retrospective study published in the Journal of Veterinary Internal Medicine examined the underlying causes of chronic diarrhea in dogs and what factors influence recovery. By reviewing 136 clinical cases, the researchers aimed to clarify how often different conditions are responsible and which findings may help predict outcomes. The study found that most cases were linked to primary intestinal disease, especially inflammatory enteropathies, with many dogs improving after treatment. These findings provide a clearer picture of how chronic diarrhea presents and progresses in real-world veterinary care.

Connecting the Dots
  • The study distinguishes between intestinal and non-intestinal causes of chronic diarrhea.
  • EPI was identified in some dogs through diagnostic testing as a secondary cause.
  • Reduced enzyme production leads to incomplete digestion, allowing undigested nutrients to reach the intestines and disrupt normal stool formation.
  • Dig Deeper

    Info Q/A's related to Exocrine Pancreatic Insufficiency (EPI)
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    Blog Articles

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