Tylosin antibiotic (Tylan Powder)

Tylosin (Tylan Powder) (Antibiotic) is a macrolide antibiotic approved for livestock but used off-label in dogs to manage chronic diarrhea and colitis, particularly antibiotic-responsive diarrhea (ARD). Its exact mechanism in gut health isn’t fully understood, but it’s believed to have anti-inflammatory and microbiome-modulating effects rather than acting purely as an antibiotic. It is typically given as a daily powder mixed with food and can be used short-term or long-term, depending on the case. Available by veterinary prescription or through farm supply stores.

Last Reviewed Date: 02/18/25